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Depression following acute myocardial infarction: a prospective relationship with ongoing health and function.

Fauerbach JA, Bush DE, Thombs BD, McCann UD, Fogel J, Ziegelstein RC

Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. JFAUERBA@JHMI.edu

The relationship between baseline depression and health-related quality of life were examined in a cohort of patients after hospitalization due to acute myocardial infarction (N=196). Patients were assessed for presence of mood disturbance, anxiety, and quality of life at the time of hospitalization and again 4 months later. Baseline assessment was used to assign subjects to a depressed or a nondepressed group. Adjusting for preinfarction quality of life, in-hospital anxiety, and demographic variables, depression was prospectively and independently related to reduced global health at 4 months as well as reduced overall mental health-including vitality, psychological health, and social function-and increased role interference from psychological problems.

Published 7 July 2005 in Psychosomatics, 46(4): 355-61.
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